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Best Resveratrol Content

Resveratrol is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. Resveratrol has many anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol is very well known in Western Europe as it can slow down the aging process. Resveratrol is found in the skin of red grapes and is a constituent of red wine. A total amount of Resveratrol per serving of wine (a 5-ounce glass) for white wines is found to be between 0.01 to 0.27 mg.

It exists as two geometric isomers: cis (Z) and trans (E), with cis-isomer. The trans form can undergo isomerisation to the cis form when exposed to ultraviolet irradiation.

Though they can undergo isomerism, but it has been found that resveratrol is very stable in plants. Trans form is more stable even in under accelerated conditions of the 75% humidity and 40 degrees C under normal atmospheric pressure. Thus resveratrol is found stable in plants grown in the hotter climates.

The mechanisms of resveratrol’s apparent effects on life extension are not fully understood, but they appear to mimic several of the biochemical effects of calories restriction. A new report indicates that resveratrol activates Sirtuin 1 (SIRT1) and PGC-1a and improves functioning of the mitochondria. Another research calls into question the theory connecting resveratrol, SIRT1, and calorie restriction.

Resveratrol content interferes with all three stages of carcinogenesis” initiation, promotion and progression. Experiments in cell cultures of varied types and isolated sub cellular systems in vitro imply many mechanisms in the pharmacological activity of resveratrol.

Resveratrol content has other benefits as well. Resveratrol content was reported effective at neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington’s disease and Alzheimer’s disease. Again, this has not yet been tested in humans for any disease.

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